High-Efficiency Disc Stack Centrifuge Technology for Biopharmaceutical Fermentation Broth Separation and Purification

With the rapid expansion of the global biopharmaceutical industry, the demand for high-purity biological products, including monoclonal antibodies, microbial metabolites, and therapeutic proteins, has continued to surge. Fermentation broth purification is a core downstream processing link that directly determines product purity, yield, and production cost. Traditional separation technologies such as plate-frame filtration and gravity sedimentation are plagued by low separation efficiency, high impurity residue, easy product activity loss, and frequent consumable replacement, which restrict the large-scale and high-quality production of biopharmaceutical products. As a high-efficiency dynamic separation equipment, disc stack centrifuges rely on density difference centrifugal separation principle, realizing rapid solid-liquid separation, impurity clarification, and active ingredient recovery under low-temperature and mild operating conditions. This paper systematically expounds on the te