Fermentation broth processing is a core procedure in bio-fermentation, enzyme preparation, food additive and functional ingredient production. Fermented crude liquid contains complex impurities including microbial cells, cell debris, residual culture medium, protein colloids and insoluble suspended solids. Traditional clarification methods such as frame filtration, static sedimentation and vacuum filtration have obvious defects, including low separation efficiency, long production cycle, large consumable loss and inevitable active ingredient loss. Sanitary disc stack centrifugal separation technology realizes high-speed solid-liquid separation relying on density difference under fully enclosed low-temperature conditions. It continuously removes microbial residues and macromolecular colloidal impurities without damaging bioactive substances, significantly improving filtrate clarity, reducing downstream membrane fouling pressure and improving product yield. This stable and efficient phys
Global edible oil manufacturers are pursuing continuous, low-loss, high-clarity refining processes to boost oil yield and extend product shelf life. Traditional separation methods including static sedimentation tanks and frame filter presses suffer from long processing cycles, high oil loss, frequent filter media replacement, and incomplete removal of gums, soapstock and free water, which severely restrict the quality and economic benefits of refined vegetable oil. Three-phase disc stack centrifuges adopt density difference centrifugal separation principle, realizing one-step simultaneous separation of oil, water and solid impurities under sealed continuous operation. This paper elaborates the working mechanism, structural advantages, standard refining process and multi-scenario application value of industrial three-phase disc centrifuges in vegetable oil production. Compared with conventional separation equipment, automated disc centrifuges deliver higher separation efficiency, lower
With the rapid expansion of the global biopharmaceutical industry, the demand for high-purity biological products, including monoclonal antibodies, microbial metabolites, and therapeutic proteins, has continued to surge. Fermentation broth purification is a core downstream processing link that directly determines product purity, yield, and production cost. Traditional separation technologies such as plate-frame filtration and gravity sedimentation are plagued by low separation efficiency, high impurity residue, easy product activity loss, and frequent consumable replacement, which restrict the large-scale and high-quality production of biopharmaceutical products. As a high-efficiency dynamic separation equipment, disc stack centrifuges rely on density difference centrifugal separation principle, realizing rapid solid-liquid separation, impurity clarification, and active ingredient recovery under low-temperature and mild operating conditions. This paper systematically expounds on the te