Nanofiltration Membrane Fine Refining Technology for Traditional Chinese Medicine Extracts

Traditional Chinese medicine crude extracts contain complex mixed impurities including soluble salts, small-molecule pigments, tannins and residual colloids after water and alcohol extraction. Traditional process methods such as repeated alcohol precipitation and high-temperature concentration often cause active ingredient loss, high residual solvent and dark color of finished medicinal liquid, failing to meet modern pharmaceutical cleanliness and stability standards. Cross-flow nanofiltration membrane technology performs selective molecular separation at room temperature, effectively removing heterozygous small-molecule impurities and excessive salt content while retaining effective TCM components. With the advantages of low energy consumption, no chemical addition and stable batch consistency, nanofiltration has become the optimal fine refining technology for standardized Chinese medicine production.