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Traditional plant extract concentration mainly relies on vacuum evaporators, which require long-term high-temperature heating. The thermal processing easily causes oxidation, browning and activity loss of heat-sensitive natural active ingredients, resulting in low product quality and low material utilization rate. In addition, thermal concentration cannot remove micro-soluble impurities, leading to high moisture ash content and poor stability of finished extracts. Nanofiltration membrane separation technology adopts low-pressure physical interception to realize efficient water removal and synchronous purification of botanical extracts at room temperature. It concentrates effective components while removing partial small-molecule impurities, greatly improving product purity, color and yield. With the advantages of energy saving, no thermal damage and stable batch consistency, nanofiltration low-temperature concentration has become an indispensable core process in modern plant deep-proce
The crude extraction liquid of traditional Chinese medicine contains extremely complex multicomponent mixtures after water extraction or alcohol extraction, including target active pharmaceutical ingredients, macromolecular colloids, residual plant fibers, tannins, inorganic salts, heteropolysaccharides and pigment impurities. Traditional refining technologies such as alcohol precipitation, resin adsorption and vacuum thermal concentration are difficult to achieve precise impurity removal, and usually cause problems such as active ingredient loss, low purification accuracy, high energy consumption, solvent residue and unstable batch quality. In modern standardized Chinese medicine pharmaceutical production, higher requirements for clarity, safety, stability and efficacy consistency have gradually eliminated outdated traditional processes. Cross-flow nanofiltration membrane separation technology relies on dual mechanisms of molecular weight screening and charge repulsion to realize low-
Traditional Chinese medicine crude extracts contain complex mixed impurities including soluble salts, small-molecule pigments, tannins and residual colloids after water and alcohol extraction. Traditional process methods such as repeated alcohol precipitation and high-temperature concentration often cause active ingredient loss, high residual solvent and dark color of finished medicinal liquid, failing to meet modern pharmaceutical cleanliness and stability standards. Cross-flow nanofiltration membrane technology performs selective molecular separation at room temperature, effectively removing heterozygous small-molecule impurities and excessive salt content while retaining effective TCM components. With the advantages of low energy consumption, no chemical addition and stable batch consistency, nanofiltration has become the optimal fine refining technology for standardized Chinese medicine production.
