2025 (Spring) China International Pharmaceutical Machinery Expositior,

In the process of biopharmaceutical production, drug components are often mixed with various impurities. Based on physical and chemical properties such as molecular size and charge nature, membrane separation technology can achieve fine separation of complex mixtures. For example, in the extraction of antibiotics, membrane separation can effectively remove impurities like host cell debris, DNA, and endotoxins, significantly increasing the purity of antibiotics and meeting high-standard drug quality requirements. Meanwhile, membrane separation uses a physical separation method, avoiding the use of high temperatures, high pressures, and chemical reagents. It provides stronger protection for the structure of drug components, and is especially suitable for the processing of heat-sensitive proteins, antibodies, and other drugs, ensuring the biological activity and stability of the drugs.

The membrane separation system features a continuous operation mode, which can remarkably enhance production efficiency. In the production of traditional Chinese medicine preparations, traditional processes often require multiple procedures and take a long time. However, membrane separation technology can simplify the process. For instance, in the preparation of traditional Chinese medicine oral liquids, the application of reverse osmosis technology can achieve efficient and rapid filtration and impurity removal of the liquid medicine, eliminating multiple procedures such as alcohol precipitation, water precipitation, concentration, and cold precipitation, greatly shortening the production cycle. This characteristic is of great significance for quickly responding to market demands and reducing production costs.

Compared with traditional processes, membrane separation technology is more economical in terms of water and energy consumption, and at the same time, it reduces the amount of waste liquid discharged. In biopharmaceutical enterprises, using membrane separation technology for wastewater treatment and material recovery can realize the recycling of resources, conforming to the development trend of green pharmaceutical production and helping enterprises achieve sustainable development. For example, treating pharmaceutical wastewater through ultrafiltration technology can not only prevent environmental pollution but also reuse the treated water as production water, saving water resources.

Membrane separation technology has extensive applications in the pharmaceutical field, covering multiple aspects such as the separation and purification of biological macromolecules, cell separation and culture, virus separation and purification, as well as the sterilization and virus removal of liquid medicine. In vaccine production, the use of affinity membrane filtration technology can achieve efficient adsorption and purification of viruses. In the drug production process, through microfiltration or nanofiltration methods, cells and cell debris in the cell culture medium can be separated, obtaining a highly pure cell culture medium. Ultrafiltration technology can also be used for sterilization and virus removal of liquid medicine while retaining the effective components of the liquid medicine.

DOUPOBIO is committed to the research, development, and application of membrane separation technology. At this Chongqing Pharmaceutical Machinery Exhibition, we will provide you with a detailed introduction to the advantages and application cases of membrane separation technology. We look forward to discussing the development prospects of membrane separation technology in the pharmaceutical industry with you and working hand in hand to promote technological innovation and sustainable development in the pharmaceutical industry.