Ultrafiltration Membrane Technology for Fermentation Broth Clarification & Fine Purification

Industrial fermentation broth contains complex mixed components including microbial cell debris, residual proteins, colloidal polymers, suspended solids and metabolic impurities after fermentation completion. Traditional clarification methods such as plate-frame filtration, vacuum filtration and centrifugal separation can only remove large particulate impurities, while tiny soluble proteins and biological colloids remain in the liquid, causing turbidity, poor stability and low product purity. In addition, traditional high-temperature concentration easily damages heat-sensitive bioactive substances and leads to low product yield. Cross-flow ultrafiltration membrane technology realizes low-temperature physical purification and precise impurity removal. It intercepts macromolecular invalid impurities and retains target active metabolites, effectively improving liquid clarity, product purity and batch stability. As an efficient and environmentally friendly refining method, ultrafiltration