Membrane separation technology including ceramic microfiltration, ultrafiltration and nanofiltration offers efficient, low-energy downstream processing solutions for complex fermentation broth. It completes cell removal, deproteinization, decolorization and concentration without heating or chemical additives, boosting product yield while cutting waste and operating costs. Widely applied in antibiotics, amino acids, organic acids and biopharmaceutical fermentation liquid treatment, integrated membrane systems deliver GMP-compliant green biomanufacturing compared with traditional centrifugation and evaporation.